Journal of Obesity & Weight Loss Therapy
91吃瓜
Our Group organises 3000+ Global Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ 91吃瓜 Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
91吃瓜 Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Citations : 2305
Indexed In
- Index Copernicus
- Google Scholar
- Open J Gate
- Genamics JournalSeek
- Centre for Agriculture and Biosciences International (CABI)
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- CABI full text
- Cab direct
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- University of Bristol
- Pubmed
- ICMJE
Useful Links
Recommended Journals
Related Subjects
Share This Page
Preventive effects of fangfengtongsheng pill on obesity through energy consumption and antiinflammatory effect
3rd International Conference and Exhibition on Obesity & Weight Management
Yingying Chen
China Pharmaceutical University, China
ScientificTracks Abstracts-Workshop: J Obes Weight Loss Ther
DOI:
Abstract
Introduction: N-truncated form of peroxisome proliferator-activated receptor-�?鲁 coactivator-1�?卤 (NT-PGC-1�?卤) is a novel truncated form of PGC-1�?卤 and contains core functional areas of PGC-1�?卤. NT-PGC-1�?卤 had become a new target for obesity treatment which plays an important role in compensation and substitution of PGC-1�?卤. Fangfengtongsheng (FFTS) pill is a traditional Chinese medicine which has anti-obesity effect and is composed of seventeen strains of herbs. However, the mechanism is not clear. Objective: To investigate the anti-obesity mechanism of FFTS from the energy metabolism and the anti-inflammatory effect. Material and methods: High-fat diet induced obese ICR mouse and brown adipose tissue primary cell were used to study the energy metabolism pathway and Raw264.7 cell was used to explore the anti-inflammatory effect. Results: Our results indicate that FFTS pill has a potential to improve the gene expression of PGC-1�?卤, NT-PGC-1�?卤 and UCP1 to increase energy expenditure, meanwhile exhibits a great reduction of TNF-�?卤,IL-6,IL-1�?虏 and iNOS expression to alleviate inflammation reaction. Conclusion: FFTS pill has a therapeutic effect on obesity through the promotion of energy consumption and inhibition of pro-inflammatory genes expression.Biography
Yingying Chen has completed her bachelor degree at the age of 23 years from Henan University of TCM and fortunately became a candidate in the Master-PhD program of China pharmaceutical University in September 2013. Her research focuses on obesity and other metabolic diseases.
Email: cmcy919925@126.com
