Our Group organises 3000+ Global Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ 91勛圖 Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Review Article
Stem Cell-Derived Neurons for the Treatment of Neurodegenerative Diseases
Haigang Gu*
Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Corresponding Author :
Haigang Gu
Department of Pharmacology
Vanderbilt University School of Medicine
Nashville, TN 37232, USA Tel: 615-343-6890 Fax: 615-343-6532 E-mail: hg.gu@vanderbilt.edu
Received April 29, 2013; Accepted June 03, 2013; Published June 05, 2013
Citation: Gu H (2013) Stem Cell-Derived Neurons for the Treatment of Neurodegenerative Diseases. Clin Pharmacol Biopharm 2:111. doi:10.4172/2167-065X.1000111
Neurodegenerative diseases are termed for the age-related chronic and progressive loss of structure and function of neurons. Most common neurodegenerative diseases include Alzheimer’s disease (AD) and Parkinson’s disease (PD). So far, no drugs can be used to reverse the neuronal degeneration. Recent progresses in stem cells biology and technology allow us to generate specific types of neurons, such as cholinergic and dopamine neurons from stem cells, with defined culture conditions. These stem cell-derived neurons have been used for cell replacement therapy in animal models of neurodegenerative neurons, such as AD and PD. Here, I summarized recent progresses of stem cell-derived cholinergic and dopamine neurons and their applications in AD and PD.
