Antenatal Depression and Risk of Complications in the Mother and the Newborn: A Retrospective Cohort Study
Abstract
Objective: To analyse the relationship between depression and complications of pregnancy and the newborn in the Lleida health region. Materials and methods: Retrospective observational cohort study in pregnant women between 2012-2018 in the Lleida health region. Variables included age, Body Mass Index (BMI), caesarean section, pre eclampsia, birth weight and Apgar score. We performed multivariate analysis, with linear regression coefficients and 95% Confidence Intervals (CI). Results: Depression was diagnosed in 2.54% pregnant women from a total sample of 17,177. Depression is significantly associated with a miscarriage (OR 1.64), higher risk pregnancy (OR 4.9) and low birth weight (OR 2.2). Pre-eclampsia, 1-minute Apgar score and caesarean section were not significantly associated with depression. Conclusion: Pregnancies in women with depression were more often classified as high-risk. In addition, depression in the mother increases the probability of miscarriage and low birth weight.
