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Maneb and Mancozeb Increase Amyloid �² Precursor Protein Expression and Activate PKR
Background: Oligomers of amyloid β (Aβ) in the brain correlate with synapse loss and dementia. The fungicide maneb (MB) and mancozeb (MZ) have been shown to activate the transcription factor NF-κB. Activation of NF-κB signaling pathway could initiate the transcription of β-amyloid precursor protein (AβPP) leading to ... Read More»
Shu-Yuan Cheng, Yessenia Lopez and Jazlene Montes
Research Article: J Cell Sci Apo 1: 110
Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article
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